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SRG is delighted to be partnering with an exciting start-up biotech company based in the Cambridge area. They are currently looking for a highly motivated Scientist to join the discovery team where you will be contributing to the development of novel TCR Therapeutics. This is a fantastic opportunity for someone looking to work in a dynamic environment and rapidly expand their knowledge and skillset.
Key Responsibilities:
Intellectual leadership of the use of high-through-put cell sorting and single cell sequencing to efficiently recover human TCRs
Designing and implementing protocols to specifically recover T cells
Sorting/screening using a multi-parameter flow cytometer to sort and analyse desired cell populations
Designing panels to further dissect T cell subsets
Development and application of LIBRA-Seq/Beam-Seq (10X Genomics) for TCR discovery
Contributing to the development of microfluidics based single cell technology for TCR discovery
Development, QC and use of in-house manufactured probes by working with protein & technology development teams
Library construction for PCR/NGS processes
Establishment, review, and updates of SOPs
Ideal Candidate:
A Ph.D. (or equivalent experience) in Immunology/Cell Biology/Molecular Biology or similar with a strong flow core/immune-assays background
Several years of postdoctoral experience in an academic or industry setting
Extensive experience in designing and testing multi-parameter panels for analysis and sorting
Extensive experience with flow analysis software (e.g. FACSDiva, FlowJo)
Significant practical laboratory experience working with primary and immortalised mammalian cell lines
Experience in design and setting up Microfluidics based assays
Experience in single cell technology and library preparation (desirable)
Demonstrated skills in trouble shooting and technology development
If you are interested in discussing the role further, then please reach out to me at / 02039379660
Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.