Lead Bioprocess Engineer - Scale-Up & Pilot Operations

Location: Somerset, UK (site-based)
Type: Full-time

We are seeking an experienced Lead Bioprocess Engineer to lead the scale-up and industrialisation of an innovative bioprocess platform. This role combines technical leadership with hands-on delivery, focusing on translating early-stage science into pilot-scale and commercially viable processes.

The Role

You will take ownership of bioprocess development and scale-up activities, working closely with R&D, engineering, and operations teams to move processes from lab through to pilot and beyond. A strong on-site presence is essential, and you will be actively involved in running experiments, troubleshooting processes, and optimising performance.

Key responsibilities include:

• Leading end-to-end scale-up activities, from bench through pilot-scale demonstration
• Translating cell culture and tissue engineering processes into scalable manufacturing solutions
• Taking a hands-on role in process optimisation, troubleshooting, and system improvements across both unit operations and the wider platform
• Designing and overseeing scale-down models and experimental plans to support robust scaling strategies
• Driving improvements in process efficiency, cost of goods, and environmental performance
• Ensuring appropriate process documentation, validation, and technical standards are maintained
• Collaborating with internal teams and external partners to support technology development and delivery
• Managing and developing a team of engineers and scientists (3-5 direct reports)

About You

You will bring a strong combination of technical depth, practical experience, and leadership capability, with a clear track record in bioprocess scale-up and industrial biotechnology.

Key requirements:

• Advanced qualification in bioprocess, biochemical, or chemical engineering
• Extensive industry experience in bioprocess development and scaling
• Proven track record working with bioreactors and associated unit operations from bench to pilot scale
• Strong understanding of upstream and/or downstream processing, including troubleshooting and optimisation
• Experience with CIP/SIP, contamination control, and operational challenges in bioprocess environments
• Demonstrated experience in leading teams and delivering complex technical programmes
• A practical, hands-on mindset, comfortable working directly with equipment and processes on-site
• A proactive, can-do attitude, with the ability to solve complex problems and adapt in a fast-paced environment

Why Apply?

This is an opportunity to play a central role in scaling a novel bioprocess technology, combining technical leadership with hands-on engineering and science. You will work in a collaborative, innovation-driven environment where your experience will directly influence the transition from R&D to real-world production.

If you are a technically strong bioprocess expert who enjoys being close to the process, leading teams, and delivering scale-up in practice, this role offers a highly impactful next step.

Guidant, Carbon60, Lorien & SRG - The Impellam Group Portfolio are acting as an Employment Business in relation to this vacancy.