The Novel Human Genetics Research Unit plays a pivotal role in the identification and validation of targets for drug discovery. The successful candidate will be performing target validation experiments in relevant cellular systems and present the analyzed data to manager and colleagues during one-on-one discussion or team meetings.
• Culture primary human cells and cell lines to support assay development.
• Run 3D cell systems and organ-on-a-chip models containing cell lines or primary human cells.
• Capture cell imaging using advanced microscopy techniques complemented by classic molecular techniques e.g. ELISA, Western, PCR, RT-PCR to characterize cell phenotype.
• Conduct experiments to investigate the biological effects of novel target genes.
• Use standard software e.g. Excel, PowerPoint, Word, GraphPad Prism, to analyze experimental data and concisely present results
• Maintain accurate and detailed laboratory notebooks according to company guidelines.
• BS or MS in Biological Sciences required with laboratory experience in cell biology and molecular biology.
• Candidate is expected to have experience in sterile mammalian cell culture, imaging cell methods and general molecular biology techniques such as RNA isolation, DNA/RNA transfection, protein quantification.
• Experience in cell-based assays and/or biochemical assays.
• Ability to execute experiment independently and work collaboratively with colleagues.
• Candidate must be able to perform independent literature research, analyze, summarize and interpret experimental data and maintain records according to company policy.
• Candidate must have the ability to cooperate with others to accomplish scientific goals and perform general maintenance duties.
SRG Woolf is an Equal Opportunity Employer - All qualified applicants will receive consideration without regard to race, color, religion, gender, national origin, age, disability, veteran status, or any other factor determined to be unlawful under applicable law.
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