Principal Scientist - Transcriptomics - new job in Cambridge, UK

Principal Scientist - Transcriptomics

Permanent

Cambridge

£ Competitive

SRG is delighted to be supporting a truly unique and innovative start-up biotech with their ongoing recruitment needs, as they continue to build their in-house research teams. Our client is focusing on the development of a highly novel synthetic biology platform to offer a range of cell therapeutics using CRISPR methodology to engineer iPSCs. Due to ongoing expansion of the business, they are now looking to appoint a Principal Scientist with a focus on Transcriptomics.

Key Responsibilities:

• Design and implement state-of-the art assays to characterise transcriptome changes, including scRNAseq and scATACseq in megakaryocytes and platelets from in vitro and in vivo platforms.
• Independent planning and execution of a wide range of robust experiments and technical studies, liaising with different teams to help guide future transcriptomics-based work streams.
• Plan, reviewing and interpret transcriptomics data, producing high-quality presentations to communicate results to senior leadership and peers.
• Contribute to authoring of technical and science reports to support IND filings.
• Work to existing SOPs and risk assessments. Contribute to generating new ones as appropriate.

Ideal candidate:

• A relevant PhD and significant experience in the areas of transcriptomics.
• Extensive experience in molecular and cell biology with expertise in genomics and transcriptome analysis.
• Experience with mammalian cell and stem cell culture.
• Proven lab-based experience with protocol design, data recording, processing, and storage.
• Excellent molecular biology skills, including library preparation for DNA and RNA sequencing.
• Hands-on experience in developing NGS, single cell or spatial transcriptomics capabilities.
• Experience in handling and analysing scRNA-seq, scATAC-seq datasets.
• Some level of management experience in mentoring and supervising junior team members.

Please apply with a copy of your CV in word or alternatively reach out for more information: Paige Keenan paige.keenan@srgtalent.com / 02039379660